My Research

My research interests are at studying solving bioinformatics problems through machine learning methods.

In order to study the functional important regions in proteins, a relational database PPIDB (Protein-Protein Interface Database) is built for the collection of protein-protein interface data. The data is published by implementing database driven web applications and web services. Protein-protein interface data can be generated through web interface query or programmatic invoking of web service functions.

An online server, SHB_PPIPS (Sequence Homologues Based Protein-Protein Interface Prediction Server) is launched as an application of the database.

Preliminary structure analysis of the protein-protein interface data has been carried out.

Classifiers designed for predicting protein-protein interface using structure properties are in progress and an online structure-based prediction server is under the way.

Kernel methods were investigated to identify interaction sites between protein-protein, protein-DNA and protein-RNA.

I had previously focused on ontology based biological data integration and learning hierarchical classifiers.