Iowa State University

Department of Computer Science

Ankit Agrawal

DNAlignTT

 

DNAlignTT: Pairwise DNA Alignment with Sequence Specific Transition-Transversion Ratio

 

Ankit Agrawal and Xiaoqiu Huang, DNAlignTT: Pairwise DNA Alignment with Sequence Specific Transition-Transversion Ratio, IEEE Intl. Conf. EIT 2008, May 18-21 pp. 457-459.

 

DNAlignTT is an iterative approach to DNA pairwise sequence alignment with sequence-specific transition-transversion ratios. In each iteration, appropriate substitution matrices are generated using the transition-transversion ratio for the given sequence pair estimated by the alignment constructed in the previous iteration. The iterations are continued until the alignment converges, or until a maximum number of iterations.

The DNAlignTT program is written in C and C++ and runs under Unix and Linux systems.
 

DNAlignTT1.0.zip