Hui-Hsien Chou
Associate Professor

Office: 503 Science II Phone: (515) 294-9242 Fax: (515) 294-8457 Email: hhchou at cs.iastate.edu (replace " at " with "@") Homepage: http://www.complex.iastate.edu/hhchou/index.html

Biographical Sketch

2005 – Present Associate Professor, Iowa State University, Ames, Iowa

1999 – 2005 Assistant Professor, Iowa State University, Ames, Iowa

1998 – 1998 Research Scientist, Celera Genomics Corporation, Rockville, Maryland

1996 – 1998 Postdoctoral Fellow, The Institute for Genomic Research (TIGR), Rockville, Maryland

1996 – 1997 Lecturer, Dept. of Computer Science, University of Maryland at College Park

Research Interests

Bioinformatics, Computational Biology, Molecular Biology, Cellular Automata, Artificial Life.

Research Areas

Bioinformatics and Computational Biology, Complex Adaptive Systems, Programming Languages and Compilers, Software Systems

Research Statement

My research interest has always been the understanding of complex systems, especially systems exhibiting lifelike behaviors. I have been working on modeling self-replication behaviors using cellular automata, a massively parallel computer-theoretical system introduced by John von Neumann in the 1950s. Cellular automata provide an alternative approach to computing which has generated great interest in computational science, artificial life and dynamic system modeling. I have also been doing studies on computational biology, the use of computing techniques to aid our better understanding of biological processes. I found these two fields complement of each other and are fascinating. In addition to these researches, I am also interested in programming languages, compilers, operating systems, computer graphics and user interfaces, genetic algorithms, neural networks and artificial intelligence.

Education

Ph.D.   University of Maryland at College Park   1996
B.S.   National Taiwan University, Taipei, Taiwan   1989
B.S.   Ming-Chih Institute of Technology, Taipei, Taiwan   1984

Representative Publications

Refereed Journal and Conference Publications

Hui-Hsien Chou. VECT: an automatic visual Perl programming tool for nonprogrammers. BioTechniques. Vol. 38. pp. 615-621, 2005.

Hui-Hsien Chou, An-Ping Hsia, Denise L. Mooney, and Patrick S. Schnable. Oligo Microarray Design for Large Genomes. Bioinformatics. Vol. 20. pp. 2893-2902, 2004.

Song Li and Hui-Hsien Chou. LUCY2: an interactive DNA sequence quality trimming and vector removal tool. Bioinformatics. Vol. 20. pp. 2865-2866, 2004.

Hui-Hsien Chou and Michael H. Holmes. DNA Sequence Quality Trimming and Vector Removal. Bioinformatics. Vol. 17. No. 12. pp. 1093−1104, 2001.

Book Chapters

Hui-Hsien Chou. Computational Methods for Microarray Design. In: Handbook of Computational Molecular Biology (Ed. Srinivas Aluru), CRC Press, Boca Raton, FL 2005.